Of All Antioxidants, Would One Finally Be Used Clinically For Atherosclerotic Disease?
Oxidation of LDL by oxygen free radicals results in unregulated uptake of modified LDL by macrophages in arterial wall. This is considered a key initiating factor for development and progression of atherosclerotic process. It is then logical to hypothesize that anti-oxidants, which can directly scav...
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| Format: | Article |
| Language: | English |
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Indonesian Heart Association
2013-10-01
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| Series: | Majalah Kardiologi Indonesia |
| Online Access: | http://ijconline.id/index.php/ijc/article/view/303 |
| Summary: | Oxidation of LDL by oxygen free radicals results in unregulated uptake of modified LDL by macrophages in arterial wall. This is considered a key initiating factor for development and progression of atherosclerotic process. It is then logical to hypothesize that anti-oxidants, which can directly scavenge free radicals, can be useful in preventing atherosclerotic process. Initial support for this hypothesis accumulated rapidly from numerous in-vitro studies. |
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| ISSN: | 0126-3773 2620-4762 |