Comparative Study of Evaluation of Therapeutic Effects of the Thyme C.W , Savory C.W. Drops and Thyme Mixture C.W. with Ranitidine – Metoclopramide Compound in Functional Dyspepsia

• Main Authors: Amir Hooshang Mohammad Alizadeh, Khosro Mani Kashani, Naser Sharafi, Mahmoud Najafian
• Format: Article
• Language: fas
• Published: Hamadan University of Medical Sciences 2001-06-01
• Series: پزشکی بالینی ابن سینا
• Subjects: functional dyspepsia – drug therapy / metoclopramide / plant therapy / ranitidine
• Online Access: http://sjh.umsha.ac.ir/article-1-884-en.html
• ISSN: 2588-722X; 2588-7238

Functional dyspepsia found in 25% of the general population and a    large number of patients referred to the health centers. Treatment of this    disease with promotility drugs is not effective, and is so expensive too.    Evaluation of therapeutic effects of the thyme C.W, savory C.W. drops and    thyme mixture in comparison with ranitidine – metoclopramide compound is    the aim of this study.           This is a randomized clinical trial study in 180 patients with dyspepsia    selected in sequential sampling with similar diet , age group and the same    smoking habit. They were randomly divided into four therapeutic groups;    the whole groups except to the fourth group used thyme C.W , savory C.W.    drops and thyme mixture C.W. with ten drops  in three times a day during a    month in a double blind method. The fourth group used ranitidine     metoclopramide compound during a month with the following orders: 1- One    tablet ranitidine every 12 hours 2- One tablet metoclopramide every 8 hours.    It is necessary to be mentioned that biopsy urease test (BUT) and histology for    evaluation of helicobacter pylori were performed in each group and each    group was divided in two subgroups that include : HP. Positive and HP.    Negative.           This study indicated that C.W. drop , savory C.W. drop , thyme mixture drop    and ranitidine – metoclopramide compound  caused disappearance of 75%    ( or more )of symptoms of disease (the complete healing) in 55.6% , 53.3% ,    42.2% and 42.2% of patients respectively.           Thyme C.W, and savory C.W. drops had the similar therapeutic effects with    that of ranitidine metoclopramide compound in the patients with functional    dyspepsia. Thyme mixture C.W. had a similar therapeutic effect with    ranitidine – metoclopramide compound. Urease positive patients gave    more response especially with the thyme C.W. drop group.