Peripheral blood stem and progenitor cell collection in pediatric candidates for ex vivo gene therapy: a 10-year series

Peripheral blood stem and progenitor cell collection in pediatric candidates for ex vivo gene therapy: a 10-year series

Hematopoietic stem and progenitor cell (HSPC)-based gene therapy (GT) requires the collection of a large number of cells. While bone marrow (BM) is the most common source of HSPCs in pediatric donors, the collection of autologous peripheral blood stem cells (PBSCs) is an attractive alternative for G...

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Bibliographic Details
Main Authors: Daniele Canarutto, Francesca Tucci, Salvatore Gattillo, Matilde Zambelli, Valeria Calbi, Bernhard Gentner, Francesca Ferrua, Sarah Marktel, Maddalena Migliavacca, Federica Barzaghi, Giulia Consiglieri, Vera Gallo, Francesca Fumagalli, Paola Massariello, Cristina Parisi, Gianluca Viarengo, Elena Albertazzi, Paolo Silvani, Raffaella Milani, Luca Santoleri, Fabio Ciceri, Maria Pia Cicalese, Maria Ester Bernardo, Alessandro Aiuti
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
plerixafor
lenograstim
apheresis
hematopoietic stem and progenitor cells
rare disease
mobilization
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000978

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