Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection.

Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection.

An effective therapeutic vaccine that could augment immune control of HIV-1 replication may abrogate or delay the need for antiretroviral therapy. AIDS Clinical Trials Group (ACTG) A5187 was a phase I/II, randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity...

Full description

Bibliographic Details
Main Authors: Eric S Rosenberg, Barney S Graham, Ellen S Chan, Ronald J Bosch, Vicki Stocker, Janine Maenza, Martin Markowitz, Susan Little, Paul E Sax, Ann C Collier, Gary Nabel, Suzanne Saindon, Theresa Flynn, Daniel Kuritzkes, Dan H Barouch, AIDS Clinical Trials Group A5187 Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2866663?pdf=render

Similar Items

Similar Items