Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates.
An UPLC-MS/MS method was developed for the determination of serotonin (5-HT), dopamine (DA), their phase I metabolites 5-HIAA, DOPAC and HVA, and their sulfate and glucuronide conjugates in human brain microdialysis samples obtained from two patients with acute brain injuries, ventricular cerebrospi...
Main Authors: | Tina Suominen, Päivi Uutela, Raimo A Ketola, Jonas Bergquist, Lars Hillered, Moshe Finel, Hongbo Zhang, Aki Laakso, Risto Kostiainen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3694921?pdf=render |
Similar Items
-
The Effect of Acupoint Application of Sinomenine for Rheumatoid Arthritis Measured by Microdialysis and UPLC-MS/MS
by: Rui Wang, et al.
Published: (2019-01-01) -
Rapid UPLC - MS/MS method for the determination of ketoprofen in human dermal microdialysis samples
by: Tettey-Amlalo, Ralph Nii Okai, et al.
Published: (2009) -
Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
by: Di Wu, et al.
Published: (2018-12-01) -
Investigating the Central Nervous System Disposition of Actinomycin D: Implementation and Evaluation of Cerebral Microdialysis and Brain Tissue Measurements Supported by UPLC-MS/MS Quantification
by: Julia Benzel, et al.
Published: (2021-09-01) -
Pesticide Screening Method with UPLC-MS/MS
by: Eriksson, Emma
Published: (2015)