Downregulation of lncRNA CCAT1 enhances 5-fluorouracil sensitivity in human colon cancer cells

Downregulation of lncRNA CCAT1 enhances 5-fluorouracil sensitivity in human colon cancer cells

Abstract Background The purpose of this study was to determine the aberrant expression of the long noncoding RNA (lncRNA) colon cancer-associated transcript 1 (CCAT1) in 5-fluorouracil-resistant colonic neoplasm cells and to elucidate its effects on the 5-fluorouracil sensitivity of human colonic ne...

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Bibliographic Details
Main Authors: Chun Yang, Yong Pan, Shao Ping Deng
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Molecular and Cell Biology
Subjects:
Colon cancer
lncRNA CCAT1
5-fluorouracil
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12860-019-0188-1

Internet

http://link.springer.com/article/10.1186/s12860-019-0188-1

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