Cholesterol intake and statin use regulate neuronal G protein-gated inwardly rectifying potassium channels
Cholesterol, a critical component of the cellular plasma membrane, is essential for normal neuronal function. Cholesterol content is highest in the brain, where most cholesterol is synthesized de novo; HMG-CoA reductase controls the synthesis rate. Despite strict control, elevated blood cholesterol...
Main Authors: | Anna N. Bukiya, Paul S. Blank, Avia Rosenhouse-Dantsker |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520326626 |
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