Irinotecan-Induced Steatohepatitis: Current Insights

Irinotecan-Induced Steatohepatitis: Current Insights

The hepatotoxicity of irinotecan is drawing wide concern nowadays due to the widespread use of this chemotherapeutic against various solid tumors, particularly metastatic colorectal cancer. Irinotecan-induced hepatotoxicity mainly manifests as transaminase increase and steatosis with or without tran...

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Bibliographic Details
Main Authors: Jun Han, Jing Zhang, Chengliang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
irinotecan
chemotherapy
hepatotoxicity
hepatic steatosis
steatohepatitis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.754891/full

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