Bioinformatics Analysis Reveals an Association Between Cancer Cell Stemness, Gene Mutations, and the Immune Microenvironment in Stomach Adenocarcinoma

Bioinformatics Analysis Reveals an Association Between Cancer Cell Stemness, Gene Mutations, and the Immune Microenvironment in Stomach Adenocarcinoma

Cancer stem cells (CSCs), characterized by infinite proliferation and self-renewal, greatly challenge tumor therapy. Research into their plasticity, dynamic instability, and immune microenvironment interactions may help overcome this obstacle. Data on the stemness indices (mRNAsi), gene mutations, c...

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Bibliographic Details
Main Authors: Zaisheng Ye, Miao Zheng, Yi Zeng, Shenghong Wei, Yi Wang, Zhitao Lin, Chen Shu, Yunqing Xie, Qiuhong Zheng, Luchuan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
stomach adenocarcinoma
cancer stemness
clinical characteristics
tumor microenvironment
tumor mutation burden
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.595477/full

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