FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by Repressing Jagged1 Expression
Summary: Mutations in FOXP1 have been linked to neurodevelopmental disorders including intellectual disability and autism; however, the underlying molecular mechanisms remain ill-defined. Here, we demonstrate with RNA and chromatin immunoprecipitation sequencing that FOXP1 directly regulates genes c...
Main Authors: | Luca Braccioli, Stephin J. Vervoort, Youri Adolfs, Cobi J. Heijnen, Onur Basak, R. Jeroen Pasterkamp, Cora H. Nijboer, Paul J. Coffer |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-11-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671117304678 |
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