Pharmacokinetics of Two Alkaloids after Oral Administration of Rhizoma Coptidis Extract in Normal Rats and Irritable Bowel Syndrome Rats
A comparative pharmacokinetic study of berberine and palmatine after oral administration of Rhizoma Coptidis extract (96 mg/kg, containing berberine 22 mg/kg and palmatine 5 mg/kg based on body weight) was performed in normal and postinflammation irritable bowel syndrome (PI-IBS) rats, induced by in...
Main Authors: | Zipeng Gong, Ying Chen, Ruijie Zhang, Yinghan Wang, Qing Yang, Yan Guo, Xiaogang Weng, Shuangrong Gao, Hailin Wang, Xiaoxin Zhu, Yu Dong, Yujie Li, Yajie Wang |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | Evidence-Based Complementary and Alternative Medicine |
Online Access: | http://dx.doi.org/10.1155/2014/845048 |
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