Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010

• Main Authors: Uchtenhagen Hannes, Sköld Annette, Sheik-Khalil Enas, Schäfer Katrein, Seifried Janna, Ruffin Nicolas, Reudelsterz Marc, Raue Katharina, Reinhart David, Palma Paolo, Mainetti Lara, Madeira Luisa, Klein Katja, Hallengärd David, van Gils Marit J, da Costa Kelly, Brinckmann Sarah, Vabret Nicolas, Ziglio Serena, Scarlatti Gabriella, Shattock Robin, Wahren Britta, Gotch Frances
• Format: Article
• Language: English
• Published: BMC 2011-04-01
• Series: Journal of Translational Medicine
• Online Access: http://www.translational-medicine.com/content/9/1/40

<p>Abstract</p> <p>Novel, exciting intervention strategies to prevent infection with HIV have been tested in the past year, and the field is rapidly evolving. EUROPRISE is a network of excellence sponsored by the European Commission and concerned with a wide range of activities including integrated developmental research on HIV vaccines and microbicides from discovery to early clinical trials. A central and timely theme of the network is the development of the unique concept of co-usage of vaccines and microbicides. This review, prepared by the PhD students of the network captures much of the research ongoing between the partners. The network is in its 5^thyear and involves over 50 institutions from 13 European countries together with 3 industrial partners; GSK, Novartis and Sanofi-Pasteur. EUROPRISE is involved in 31 separate world-wide trials of Vaccines and Microbicides including 6 in African countries (Tanzania, Mozambique, South Africa, Kenya, Malawi, Rwanda), and is directly supporting clinical trials including MABGEL, a gp140-hsp70 conjugate trial and HIVIS, vaccine trials in Europe and Africa.</p>