Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs
This study aimed to determine the power of the serum aspartate aminotransferase (AST) and gamma-glutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred...
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Universidade Federal de Minas Gerais
2012-12-01
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Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
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doaj-79a33d5cc0294881a116a282328950492020-11-24T22:45:12ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622012-12-016461403141010.1590/S0102-09352012000600001S0102-09352012000600001Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signsC.N. Moreira0S.N. Souza1A.C. Barini2E.G. Araújo3M.C.S. Fioravanti4Universidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásThis study aimed to determine the power of the serum aspartate aminotransferase (AST) and gamma-glutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred were evaluated. Blood and liver samples were collected on the day of slaughter for biochemical and histopathological tests. The results showed that the sensitivity to AST, GGT, albumin, and cholesterol tests were respectively 22.4%, 22.4%, 36%, and 37.2%. The specificity of AST, GGT, albumin, and cholesterol tests was respectively 78.8%, 90.4%, 75.6%, and 68.3%. In short, the detection of minor liver injuries through biochemical tests is limited; however, the high specificity of the GGT allows its use as an indicator of hepatic chronic injuries in cattle herds.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600001&lng=en&tlng=engado de cortealbuminaASTcolesterolbioquímica clínicaGGT |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
C.N. Moreira S.N. Souza A.C. Barini E.G. Araújo M.C.S. Fioravanti |
spellingShingle |
C.N. Moreira S.N. Souza A.C. Barini E.G. Araújo M.C.S. Fioravanti Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs Arquivo Brasileiro de Medicina Veterinária e Zootecnia gado de corte albumina AST colesterol bioquímica clínica GGT |
author_facet |
C.N. Moreira S.N. Souza A.C. Barini E.G. Araújo M.C.S. Fioravanti |
author_sort |
C.N. Moreira |
title |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_short |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_full |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_fullStr |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_full_unstemmed |
Serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
title_sort |
serum γ-glutamyltransferase activity as an indicator of chronic liver injury in cattle with no clinical signs |
publisher |
Universidade Federal de Minas Gerais |
series |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
issn |
1678-4162 |
publishDate |
2012-12-01 |
description |
This study aimed to determine the power of the serum aspartate aminotransferase (AST) and gamma-glutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred were evaluated. Blood and liver samples were collected on the day of slaughter for biochemical and histopathological tests. The results showed that the sensitivity to AST, GGT, albumin, and cholesterol tests were respectively 22.4%, 22.4%, 36%, and 37.2%. The specificity of AST, GGT, albumin, and cholesterol tests was respectively 78.8%, 90.4%, 75.6%, and 68.3%. In short, the detection of minor liver injuries through biochemical tests is limited; however, the high specificity of the GGT allows its use as an indicator of hepatic chronic injuries in cattle herds. |
topic |
gado de corte albumina AST colesterol bioquímica clínica GGT |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600001&lng=en&tlng=en |
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