2-(2-(4-Benzoylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives: Synthesis, docking and acetylcholinesterase inhibitory evaluation as anti-alzheimer agents

2-(2-(4-Benzoylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives: Synthesis, docking and acetylcholinesterase inhibitory evaluation as anti-alzheimer agents

Objective(s): Alzheimer’s disease (AD) as progressive cognitive decline and the most common form of dementia is due to degeneration of the cholinergic neurons in the brain. Therefore, administration of the acetylcholinesterase (AChE) inhibitors such as donepezil is the first choice for treatment of...

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Bibliographic Details
Main Authors:	Ahmad Mohammadi-Farani, Nasibeh Abdi, Alireza Moradi, Alireza Aliabadi
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2017-01-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	Acetylcholinesterase Alzheimer Docking Ellman test Phthalimide Synthesis
Online Access:	http://ijbms.mums.ac.ir/article_8095_9b849f9c700eef1c7704230c6bb85d5b.pdf

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