Endogenous retroviruses as targets for antitumor immunity in renal cell cancer and other tumors

Human endogenous retroviruses (HERVs), remnants of ancient germ-line infections with exogenous retroviruses, are estimated to comprise up to 8% of human genome. Most HERVs have accumulated mutations and deletions that prevent their expression as an infectious virus. Nevertheless, a growing number of...

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Bibliographic Details
Main Authors: Elena eCherkasova, Quinn eWeisman, Richard W. Childs
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00243/full