Human Muscle Progenitor Cells Overexpressing Neurotrophic Factors Improve Neuronal Regeneration in a Sciatic Nerve Injury Mouse Model

Human Muscle Progenitor Cells Overexpressing Neurotrophic Factors Improve Neuronal Regeneration in a Sciatic Nerve Injury Mouse Model

The peripheral nervous system has an intrinsic ability to regenerate after injury. However, this process is slow, incomplete, and often accompanied by disturbing motor and sensory consequences. Sciatic nerve injury (SNI), which is the most common model for studying peripheral nerve injury, is charac...

Full description

Bibliographic Details
Main Authors: Reut Guy, Frida Grynspan, Tali Ben-Zur, Avraham Panski, Ron Lamdan, Uri Danon, David Yaffe, Daniel Offen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroscience
Subjects:
human muscle progenitor cells
neurotrophic factors
BDNF
GDNF
VEGF
IGF-1
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00151/full

Similar Items

Similar Items