Process Intensification for an Insect Antimicrobial Peptide Elastin-Like Polypeptide Fusion Produced in Redox-Engineered Escherichia coli

Peptides and proteins containing disulfide bonds can be produced in Escherichia coli by targeting the oxidizing periplasm, co-expressing isomerases or chaperons, refolding from inclusion bodies, or by using redox-engineered E. coli strains. Thus far, protein expression in glutathione reductase and t...

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Bibliographic Details
Main Authors: Mathias Joachim, Nicolas Maguire, Johannes Schäfer, Doreen Gerlach, Peter Czermak
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00150/full

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