Malignant gastrointestinal stromal tumor in association with Russell body gastritis—A case report

• Main Authors: Desislava M Bozhkova, Maria S Koleva-Ivanova, Veselin T Belovejdov, Dorian I Dikov
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: Indian Journal of Pathology and Microbiology
• Subjects: gastrointestinal stromal tumors; helicobacter pylori; plasma cells; russell body gastritis; stomach
• Online Access: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=89;epage=91;aulast=Bozhkova

Russell body gastritis (RBG) is an unusual form of chronic inflammation characterized by accumulation of plasma cells containing Russell bodies (RB) in the gastric mucosa. Although its pathogenesis has not been fully evaluated, there is evidence to support a strong association with Helicobacter pylori infection. Only four cases of RBG in association with malignant epithelial gastric tumors were reported. We report the first case of RBG in peritumoral mucosa of a malignant gastrointestinal stromal tumor in association with coccoid form of Helicobacter pylori and a follow-up.