Senescent T cells: a potential biomarker and target for cancer therapy
The failure of T cells to eradicate tumour cells in the tumour microenvironment is mainly due to the dysfunction of T cells. Senescent T cells, with defects in proliferation and effector functions, accumulate in ageing, chronic viral infections, and autoimmune disorders where antigen stimulation per...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-06-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396421002024 |