Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction
AIM: To estimate the informative value of multislice spiral computed tomography (MSCT) in the diagnosis of myocardial infarction (MI)/MATERIAL AND METHODS: The study enrolled 171 patients with acute coronary syndrome (ACS), including 121 patients diagnosed with acute ST-segment elevation MI (STEMI),...
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doaj-7a0d055025c94a3b988391edb2a86b3a2020-11-25T03:04:45Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422013-04-01854162128231Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarctionT N VeselovaS K TernovoĭAIM: To estimate the informative value of multislice spiral computed tomography (MSCT) in the diagnosis of myocardial infarction (MI)/MATERIAL AND METHODS: The study enrolled 171 patients with acute coronary syndrome (ACS), including 121 patients diagnosed with acute ST-segment elevation MI (STEMI), 19 with non-STEMI, and 31 with unstable angina. A comparison group consisted of 52 patients with stable coronary heart disease (CHD) and a control group comprised 17 patients without CHD. Intravenous contrast-enhanced MSCT was performed using a 64-spiral CT scanner. MSCT was carried out in the patients with ACS on days 3-5 of the onset of a pain attack and in the other patients electively. It was redone in 44 patients with acute MI (AMI) 6 months after a primary examination/RESULTS: Left ventricular (LV) perfusion defect was imaged in 94.3% of the patients with AMI and in 10% of those with unstable angina. LV contrast defects were undetectable in the patients from the stable CHD and control groups. The sensitivity, specificity, prognostic value of a positive result, negative prognostic value of a result, and accuracy of MSCT in the diagnosis of MI were 94.3, 97.1, 97.8, 92.5, and 96.7%, respectively. In the patients with STEMI, myocardial perfusion defect was larger and transmural perfusion defect was more common than in those with non-STEMI. Comparison of the values of myocardial perfusion defect size and myocardial density according to the data of primary and repeat MSCT revealed no statistically significant differences: 2.0 (0.50; 5.45) and 1,8 (0.35; 5.00) cm3 (p=0.15); 41.7±10.2 and 46.1±12.2 HU, respectively (p=0.07)/CONCLUSION: Contrast-enhanced MSCT allows visual and quantitative assessments of myocardial perfusion defect in patients with ACS. Myocardial perfusion defect from MSCT data suggests previous MI with a high probability, but does not permit the determination of the duration of the disease.https://ter-arkhiv.ru/0040-3660/article/view/31215multislice spiral computed tomographymyocardial infarctionperfusion defect |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
T N Veselova S K Ternovoĭ |
spellingShingle |
T N Veselova S K Ternovoĭ Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction Терапевтический архив multislice spiral computed tomography myocardial infarction perfusion defect |
author_facet |
T N Veselova S K Ternovoĭ |
author_sort |
T N Veselova |
title |
Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction |
title_short |
Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction |
title_full |
Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction |
title_fullStr |
Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction |
title_full_unstemmed |
Informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction |
title_sort |
informative value of multislice spiral computed tomography in identifying myocardial perfusion defect in patients with acute myocardial infarction |
publisher |
"Consilium Medicum" Publishing house |
series |
Терапевтический архив |
issn |
0040-3660 2309-5342 |
publishDate |
2013-04-01 |
description |
AIM: To estimate the informative value of multislice spiral computed tomography (MSCT) in the diagnosis of myocardial infarction (MI)/MATERIAL AND METHODS: The study enrolled 171 patients with acute coronary syndrome (ACS), including 121 patients diagnosed with acute ST-segment elevation MI (STEMI), 19 with non-STEMI, and 31 with unstable angina. A comparison group consisted of 52 patients with stable coronary heart disease (CHD) and a control group comprised 17 patients without CHD. Intravenous contrast-enhanced MSCT was performed using a 64-spiral CT scanner. MSCT was carried out in the patients with ACS on days 3-5 of the onset of a pain attack and in the other patients electively. It was redone in 44 patients with acute MI (AMI) 6 months after a primary examination/RESULTS: Left ventricular (LV) perfusion defect was imaged in 94.3% of the patients with AMI and in 10% of those with unstable angina. LV contrast defects were undetectable in the patients from the stable CHD and control groups. The sensitivity, specificity, prognostic value of a positive result, negative prognostic value of a result, and accuracy of MSCT in the diagnosis of MI were 94.3, 97.1, 97.8, 92.5, and 96.7%, respectively. In the patients with STEMI, myocardial perfusion defect was larger and transmural perfusion defect was more common than in those with non-STEMI. Comparison of the values of myocardial perfusion defect size and myocardial density according to the data of primary and repeat MSCT revealed no statistically significant differences: 2.0 (0.50; 5.45) and 1,8 (0.35; 5.00) cm3 (p=0.15); 41.7±10.2 and 46.1±12.2 HU, respectively (p=0.07)/CONCLUSION: Contrast-enhanced MSCT allows visual and quantitative assessments of myocardial perfusion defect in patients with ACS. Myocardial perfusion defect from MSCT data suggests previous MI with a high probability, but does not permit the determination of the duration of the disease. |
topic |
multislice spiral computed tomography myocardial infarction perfusion defect |
url |
https://ter-arkhiv.ru/0040-3660/article/view/31215 |
work_keys_str_mv |
AT tnveselova informativevalueofmultislicespiralcomputedtomographyinidentifyingmyocardialperfusiondefectinpatientswithacutemyocardialinfarction AT skternovoi informativevalueofmultislicespiralcomputedtomographyinidentifyingmyocardialperfusiondefectinpatientswithacutemyocardialinfarction |
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