Incidental Metastatic Meningioma Presenting as a Large Liver Mass

Meningiomas are slow growing neoplasms of the central nervous system (CNS). Most of the tumors are benign and distant metastasis from a benign meningioma is rare. Metastasis to the liver, although rare, usually presents with hypoglycemia or occurs in conjunction with a clinical history of an intracr...

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Main Authors: Ifeyinwa E. Obiorah, Metin Ozdemirli
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Hepatology
Online Access:http://dx.doi.org/10.1155/2018/1089394
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spelling doaj-7a2013153c824d9a95aacaefd0e4f1842020-11-24T21:04:02ZengHindawi LimitedCase Reports in Hepatology2090-65872090-65952018-01-01201810.1155/2018/10893941089394Incidental Metastatic Meningioma Presenting as a Large Liver MassIfeyinwa E. Obiorah0Metin Ozdemirli1Department of Pathology, MedStar Georgetown University Hospital, Washington, DC, USADepartment of Pathology, MedStar Georgetown University Hospital, Washington, DC, USAMeningiomas are slow growing neoplasms of the central nervous system (CNS). Most of the tumors are benign and distant metastasis from a benign meningioma is rare. Metastasis to the liver, although rare, usually presents with hypoglycemia or occurs in conjunction with a clinical history of an intracranial meningioma or following the resection of a prior CNS meningioma, thus making clinical diagnosis relatively easy. Here we present an unusual case of metastatic meningioma to the liver in a 54-year-old female who presented with an incidental liver mass by ultrasound. Her clinical history and physical examination were unremarkable. A partial hepatectomy revealed a meningioma on histology. Further investigation by imaging studies showed a frontal parasagittal dural mass which was confirmed to be a World Health Organization (WHO) grade 1 meningioma. To our knowledge, this is the first report of a clinically silent metastatic meningioma to the liver without either a concurrent or a previous history of meningioma. Precise diagnosis of this challenging case requires high clinical suspicion, histopathology, and immunohistochemistry.http://dx.doi.org/10.1155/2018/1089394
collection DOAJ
language English
format Article
sources DOAJ
author Ifeyinwa E. Obiorah
Metin Ozdemirli
spellingShingle Ifeyinwa E. Obiorah
Metin Ozdemirli
Incidental Metastatic Meningioma Presenting as a Large Liver Mass
Case Reports in Hepatology
author_facet Ifeyinwa E. Obiorah
Metin Ozdemirli
author_sort Ifeyinwa E. Obiorah
title Incidental Metastatic Meningioma Presenting as a Large Liver Mass
title_short Incidental Metastatic Meningioma Presenting as a Large Liver Mass
title_full Incidental Metastatic Meningioma Presenting as a Large Liver Mass
title_fullStr Incidental Metastatic Meningioma Presenting as a Large Liver Mass
title_full_unstemmed Incidental Metastatic Meningioma Presenting as a Large Liver Mass
title_sort incidental metastatic meningioma presenting as a large liver mass
publisher Hindawi Limited
series Case Reports in Hepatology
issn 2090-6587
2090-6595
publishDate 2018-01-01
description Meningiomas are slow growing neoplasms of the central nervous system (CNS). Most of the tumors are benign and distant metastasis from a benign meningioma is rare. Metastasis to the liver, although rare, usually presents with hypoglycemia or occurs in conjunction with a clinical history of an intracranial meningioma or following the resection of a prior CNS meningioma, thus making clinical diagnosis relatively easy. Here we present an unusual case of metastatic meningioma to the liver in a 54-year-old female who presented with an incidental liver mass by ultrasound. Her clinical history and physical examination were unremarkable. A partial hepatectomy revealed a meningioma on histology. Further investigation by imaging studies showed a frontal parasagittal dural mass which was confirmed to be a World Health Organization (WHO) grade 1 meningioma. To our knowledge, this is the first report of a clinically silent metastatic meningioma to the liver without either a concurrent or a previous history of meningioma. Precise diagnosis of this challenging case requires high clinical suspicion, histopathology, and immunohistochemistry.
url http://dx.doi.org/10.1155/2018/1089394
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