Endothelial Dysfunction in Steatotic Human Donor Livers: A Pilot Study of the Underlying Mechanism During Subnormothermic Machine Perfusion
Background. Steatosis is a major risk factor for primary nonfunction in liver transplantations. Steatotic livers recover poorly from ischemia reperfusion injury, in part due to alterations in the microcirculation, although the exact mechanism is unclear. In this study, we tested if there were any al...
Main Authors: | Irene Beijert, MD, Safak Mert, PhD, Viola Huang, MD, Negin Karimian, MD, Sharon Geerts, BSc, Ehab O.A. Hafiz, MD, James F. Markmann, MD, Heidi Yeh, MD, Robert J. Porte, MD, PhD, Korkut Uygun, PhD |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2018-05-01
|
Series: | Transplantation Direct |
Online Access: | http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000779 |
Similar Items
-
Subnormothermic Machine Perfusion of Steatotic Livers Results in Increased Energy Charge at the Cost of Anti-Oxidant Capacity Compared to Normothermic Perfusion
by: Negin Karimian, et al.
Published: (2019-10-01) -
A Comparative Study of Single and Dual Perfusion During End-ischemic Subnormothermic Liver Machine Preservation
by: Isabel M.A. Brüggenwirth, BSc, et al.
Published: (2018-11-01) -
Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies.
by: Siavash Raigani, et al.
Published: (2020-01-01) -
Anatomical Study of Perfusion of a Periosteal Flap with a Lateral Pedicle
by: Boktae Kim, MD, et al.
Published: (2017-09-01) -
Left ventricular function and myocardial perfusion before and after cardiac resynchronization therapy in chronic right ventricular apical pacing by echocardiogram-gated myocardial perfusion single photon emission computed tomography
by: Yuki Honda, MD, et al.
Published: (2012-04-01)