TLR2 directing PD-L2 expression inhibit T cells response in Schistosoma japonicum infection.

TLR2 directing PD-L2 expression inhibit T cells response in Schistosoma japonicum infection.

Toll-like receptor 2 (TLR2) was shown to be an important immune receptor involved in the recognition of schistosome antigens, especially soluble egg antigen (SEA). In mice models with Schistosoma japonicum acute infection, we observed enhanced T cell-mediated immune responses in TLR2 knock out (TLR2...

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Bibliographic Details
Main Authors: Yanan Gao, Lin Chen, Min Hou, Yingying Chen, Minjun Ji, Haiwei Wu, Guanling Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869711?pdf=render

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