Monoclonal Antibodies Against Human Papillomavirus E6 and E7 Oncoproteins Inhibit Tumor Growth in Experimental Cervical Cancer

Monoclonal Antibodies Against Human Papillomavirus E6 and E7 Oncoproteins Inhibit Tumor Growth in Experimental Cervical Cancer

Nearly all cases of cervical cancer are initiated by persistent infection with high-risk strains of human papillomavirus (hr-HPV). When hr-HPV integrates into the host genome, the constitutive expression of oncogenic HPV proteins E6 and E7 function to disrupt p53 and retinoblastoma regulation of cel...

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Bibliographic Details
Main Authors:	Zewei Jiang, Joseph Albanese, Joshua Kesterson, Joshua Warrick, Rouzan Karabakhtsian, Ekaterina Dadachova, Rébécca Phaëton
Format:	Article
Language:	English
Published:	Elsevier 2019-10-01
Series:	Translational Oncology
Online Access:	http://www.sciencedirect.com/science/article/pii/S193652331930018X

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