Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations
Abstract Protein stability is a requisite in the field of biotechnology, cell biology and drug design. To understand effects of amino acid substitutions, computational models are preferred to save time and expenses. As a systemically important, highly abundant, stable protein, the knowledge of Cu/Zn...
Main Authors: | Vijay Kumar, Safikur Rahman, Hani Choudhry, Mazin A. Zamzami, Mohammad Sarwar Jamal, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-04950-9 |
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