Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities

Silver nanoparticles (Ag-NPs) synthesized through reduction by Otostegia limbata green extract are, hereby, reported for the first time. It is very interesting to observe that in this case, O. limbata plant extract acts as a strong chelating agent in Ag-NPs formation through AgNO3. Scanning electron...

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Main Authors:	Rizwan Kausar, Muhammad Ashraf Shaheen, Qaisar Maqbool, Sania Naz, Mudassar Nazar, Fazal Abbas, Talib Hussain, Umer Younas, Muhammad Fahad Shams
Format:	Article
Language:	English
Published:	AIP Publishing LLC 2016-09-01
Series:	AIP Advances
Online Access:	http://dx.doi.org/10.1063/1.4962660

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spelling	doaj-7a7d2914852540e3a048bd9fba327b6e2020-11-25T00:41:47ZengAIP Publishing LLCAIP Advances2158-32262016-09-0169095203095203-810.1063/1.4962660013609ADVFacile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activitiesRizwan Kausar0Muhammad Ashraf Shaheen1Qaisar Maqbool2Sania Naz3Mudassar Nazar4Fazal Abbas5Talib Hussain6Umer Younas7Muhammad Fahad Shams8Department of Chemistry, University of Sargodha, Sargodha 40100, PakistanDepartment of Chemistry, University of Sargodha, Sargodha 40100, PakistanDepartment of Biotechnology, Virtual University of Pakistan, Lahore 54000, PakistanPreston Institute of Nano Science and Nanotechnology (PINSAT), Preston University, Islamabad 44000, PakistanDepartment of Biotechnology, Virtual University of Pakistan, Lahore 54000, PakistanInterdisciplinary Research Organization, University of Chakwal (UOC), Chakwal 48800, PakistanNational Institute of Vacuum Science and Technology (NINVAST), Islamabad 44000, PakistanDepartment of Chemistry, University of Sargodha, Sargodha 40100, PakistanPreston Institute of Nano Science and Nanotechnology (PINSAT), Preston University, Islamabad 44000, PakistanSilver nanoparticles (Ag-NPs) synthesized through reduction by Otostegia limbata green extract are, hereby, reported for the first time. It is very interesting to observe that in this case, O. limbata plant extract acts as a strong chelating agent in Ag-NPs formation through AgNO3. Scanning electron microscope (SEM) studies expose that Ag-NPs formation is highly homogenous and spherical with mean particle size of 32±0.8 nm. A typical Ag absorption peak has been observed at 419 nm by ultra violet (UV)-visible spectroscopy which have endorsed the successful formation of single phase Ag-NPs. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) examination further validates the crystalline pure phase structure of Ag-NPs. Promising results have been recorded against protein kinase inhibition assay and antibacterial assay having prominent pathogenic strains. Our present study explores that biosynthesized eco-friendly Ag-NPs have great potential, in the future, for anticancer drug development with wide range pharmaceutical applications.http://dx.doi.org/10.1063/1.4962660
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Rizwan Kausar Muhammad Ashraf Shaheen Qaisar Maqbool Sania Naz Mudassar Nazar Fazal Abbas Talib Hussain Umer Younas Muhammad Fahad Shams
spellingShingle	Rizwan Kausar Muhammad Ashraf Shaheen Qaisar Maqbool Sania Naz Mudassar Nazar Fazal Abbas Talib Hussain Umer Younas Muhammad Fahad Shams Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities AIP Advances
author_facet	Rizwan Kausar Muhammad Ashraf Shaheen Qaisar Maqbool Sania Naz Mudassar Nazar Fazal Abbas Talib Hussain Umer Younas Muhammad Fahad Shams
author_sort	Rizwan Kausar
title	Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities
title_short	Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities
title_full	Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities
title_fullStr	Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities
title_full_unstemmed	Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities
title_sort	facile biosynthesis of ag-nps using otostegia limbata plant extract: physical characterization and auspicious biological activities
publisher	AIP Publishing LLC
series	AIP Advances
issn	2158-3226
publishDate	2016-09-01
description	Silver nanoparticles (Ag-NPs) synthesized through reduction by Otostegia limbata green extract are, hereby, reported for the first time. It is very interesting to observe that in this case, O. limbata plant extract acts as a strong chelating agent in Ag-NPs formation through AgNO3. Scanning electron microscope (SEM) studies expose that Ag-NPs formation is highly homogenous and spherical with mean particle size of 32±0.8 nm. A typical Ag absorption peak has been observed at 419 nm by ultra violet (UV)-visible spectroscopy which have endorsed the successful formation of single phase Ag-NPs. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) examination further validates the crystalline pure phase structure of Ag-NPs. Promising results have been recorded against protein kinase inhibition assay and antibacterial assay having prominent pathogenic strains. Our present study explores that biosynthesized eco-friendly Ag-NPs have great potential, in the future, for anticancer drug development with wide range pharmaceutical applications.
url	http://dx.doi.org/10.1063/1.4962660
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Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities

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