Dedifferentiated chondrosarcoma of right proximal femur

• Main Authors: Sachin A Badge, Nitin M Gangane, Vitaladevnni B Shivkumar, Satish M Sharma
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2016-01-01
• Series: Medical Journal of Dr. D.Y. Patil University
• Subjects: Chondrosarcoma; dedifferentiated; sarcoma
• Online Access: http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=2;spage=261;epage=263;aulast=Badge

Dedifferentiated chondrosarcoma (DDCS) comprises approximately 10% of all chondrosarcomas. The tumor generally occurs after the age of 50 years, with equal distribution among males and females. It is most often located in the bones of the pelvis, the proximal femur or humerus, the distal femur, and the ribs. Regardless of treatment, the prognosis is ominous with 90% of patients dying with distant metastases within 2 years. We report a case of DDCS of right proximal femur in a 73-year-old woman. The most important factors affecting survival are early recognition of the radiographic features, adequate histological sampling, and wide-margin resection of the lesion. So for the correct histopathological diagnosis the biopsy sample should be adequate to visualize both cartilaginous and noncartilaginous sarcomatous component which helps to increase the survival of patients before the distant metastasis occurs.