Histone-like nucleoid-structuring protein (H-NS) regulatory role in antibiotic resistance in Acinetobacter baumannii

Histone-like nucleoid-structuring protein (H-NS) regulatory role in antibiotic resistance in Acinetobacter baumannii

Abstract In the multidrug resistant (MDR) pathogen Acinetobacter baumannii the global repressor H-NS was shown to modulate the expression of genes involved in pathogenesis and stress response. In addition, H-NS inactivation results in an increased resistance to colistin, and in a hypermotile phenoty...

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Main Authors: Deja Rodgers, Casin Le, Camila Pimentel, Marisel R. Tuttobene, Tomás Subils, Jenny Escalante, Brent Nishimura, Eleonora García Vescovi, Rodrigo Sieira, Robert A. Bonomo, Marcelo E. Tolmasky, Maria Soledad Ramirez
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98101-w

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