Serum-Free Medium Enhances the Therapeutic Effects of Umbilical Cord Mesenchymal Stromal Cells on a Murine Model for Acute Colitis

Serum-Free Medium Enhances the Therapeutic Effects of Umbilical Cord Mesenchymal Stromal Cells on a Murine Model for Acute Colitis

The usage of animal serum may ultimately prevent the application of ex vivo cultured mesenchymal stromal cells (MSCs) in a clinical setting due to safety concerns and batch-to-batch variability. Increasing regulatory pressure to limit use of animal serum has been issued and serum-free, xeno-free, an...

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Bibliographic Details
Main Authors: Xiaoyun Wu, Daocheng Wu, Yongxu Mu, Yuxia Zhao, Zhijie Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stromal cells
colitis
therapeutic effect
mechanism
serum free
macrophage polarization
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00586/full

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