Summary: | No abstract available. Article truncated at 150 words. Shah PL, Zoumot Z, Singh S, Bicknell SR, Ross ET, Quiring J, Hopkinson NS, Kemp SV for the RESET trial Study Group. endobronchial coils for the treatment of severe emphysema with hyperinflation (RESET): a randomised controlled trial. Lancet Respiratory Medicine. 2013;1(3):233-40. AbstractDespite advances in pharmacologic therapies, chronic obstructive pulmonary disease (COPD) remains a challenging respiratory disease. It is currently the third leading cause of death. Prior invasive treatment strategies such as endobronchial valves and surgical lung volume reduction have had limited success. Surgical lung volume reduction remains an option in patients with heterogeneous upper lobe predominant emphysema, poor exercise tolerance and FEV1 < 35% (1). The placement of endobronchial coils has been studied in smaller cohort studies and shown to reduce hyperinflation. This study is a larger randomized control trial looking at the efficacy and safety of endobronchial lung volume reduction coils (LRVC). The study was performed between January…
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