Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots
The chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 1–3 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were establi...
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MDPI AG
2017-12-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/23/1/80 |
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doaj-7aedd5bd716e4a058b074b4ceb8813212020-11-24T21:48:27ZengMDPI AGMolecules1420-30492017-12-012318010.3390/molecules23010080molecules23010080Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada RootsNabila Zergainoh0Maria Letizia Ciavatta1Marianna Carbone2Fatma Bitam3Mohamed Cherif Aberkane4Margherita Gavagnin5National Research Council (CNR), Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli (Naples), ItalyNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli (Naples), ItalyNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli (Naples), ItalyDepartment of Pharmacy, University of Batna 2, Faculty of Medicine, 05000 Batna, AlgeriaLaboratory of Chemistry and Environmental Chemistry (L.C.C.E), Department of Chemistry, Faculty of Sciences of the Matter, University of Batna 1, 05000 Batna, AlgeriaNational Research Council (CNR), Institute of Biomolecular Chemistry (ICB), Via Campi Flegrei, 34, 80078 Pozzuoli (Naples), ItalyThe chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 1–3 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were established by spectroscopic methods, including NMR techniques. The chemical pattern of L. acanthoclada is in accordance with the triterpenoid scenario of the genus Launaea embracing to date lupane, oleane, ursane and taraxastane skeletons. However, the carbon frameworks exhibited by new compounds 1–3 have never been reported from Launaea species.https://www.mdpi.com/1420-3049/23/1/80Launaea acanthocladatriterpenoidslupanebaueranestructural elucidationNMR |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Nabila Zergainoh Maria Letizia Ciavatta Marianna Carbone Fatma Bitam Mohamed Cherif Aberkane Margherita Gavagnin |
| spellingShingle |
Nabila Zergainoh Maria Letizia Ciavatta Marianna Carbone Fatma Bitam Mohamed Cherif Aberkane Margherita Gavagnin Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots Molecules Launaea acanthoclada triterpenoids lupane bauerane structural elucidation NMR |
| author_facet |
Nabila Zergainoh Maria Letizia Ciavatta Marianna Carbone Fatma Bitam Mohamed Cherif Aberkane Margherita Gavagnin |
| author_sort |
Nabila Zergainoh |
| title |
Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots |
| title_short |
Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots |
| title_full |
Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots |
| title_fullStr |
Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots |
| title_full_unstemmed |
Exploring the Chemical Diversity of Algerian Plants: Three New Pentacyclic Triterpenoids from Launaea acanthoclada Roots |
| title_sort |
exploring the chemical diversity of algerian plants: three new pentacyclic triterpenoids from launaea acanthoclada roots |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2017-12-01 |
| description |
The chemical study of Launaea acanthoclada from South-East Algeria led to the isolation of twelve oxygenated terpenoid compounds, including three new pentacyclic triterpenoids 1–3 with either lupane or ursane rearranged skeletons. The structure and the stereochemistry of these compounds were established by spectroscopic methods, including NMR techniques. The chemical pattern of L. acanthoclada is in accordance with the triterpenoid scenario of the genus Launaea embracing to date lupane, oleane, ursane and taraxastane skeletons. However, the carbon frameworks exhibited by new compounds 1–3 have never been reported from Launaea species. |
| topic |
Launaea acanthoclada triterpenoids lupane bauerane structural elucidation NMR |
| url |
https://www.mdpi.com/1420-3049/23/1/80 |
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