Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells agains...
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doaj-7af8a72760ae4af2b6347cc9d56766162020-11-24T23:21:01ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882014-01-01201410.1155/2014/726724726724Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic RatsAriyo Movahedi0Rusliza Basir1Asmah Rahmat2Mohammad Charaffedine3Fauziah Othman4Department of Nutrition and Dietetics, Faculty of Medicine, Universiti Putra Malaysia, MalaysiaDepartment of Human Anatomy, Faculty of Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaDepartment of Nutrition and Dietetics, Faculty of Medicine, Universiti Putra Malaysia, MalaysiaDiseased Tissue Pathology Laboratory, Tyre, LebanonDepartment of Human Anatomy, Faculty of Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, MalaysiaThe term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development.http://dx.doi.org/10.1155/2014/726724 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ariyo Movahedi Rusliza Basir Asmah Rahmat Mohammad Charaffedine Fauziah Othman |
spellingShingle |
Ariyo Movahedi Rusliza Basir Asmah Rahmat Mohammad Charaffedine Fauziah Othman Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats Evidence-Based Complementary and Alternative Medicine |
author_facet |
Ariyo Movahedi Rusliza Basir Asmah Rahmat Mohammad Charaffedine Fauziah Othman |
author_sort |
Ariyo Movahedi |
title |
Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_short |
Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_full |
Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_fullStr |
Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_full_unstemmed |
Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_sort |
remarkable anticancer activity of teucrium polium on hepatocellular carcinogenic rats |
publisher |
Hindawi Limited |
series |
Evidence-Based Complementary and Alternative Medicine |
issn |
1741-427X 1741-4288 |
publishDate |
2014-01-01 |
description |
The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development. |
url |
http://dx.doi.org/10.1155/2014/726724 |
work_keys_str_mv |
AT ariyomovahedi remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT ruslizabasir remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT asmahrahmat remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT mohammadcharaffedine remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT fauziahothman remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats |
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1725572988726673408 |