Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma.

Epigenetic modifications are important early events during carcinogenesis. In particular, hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a well-known mechanism of gene silencing that contributes to cancer development and progression. Tissue factor pathway inhibit...

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Bibliographic Details
Main Authors: Serena Ferraresso, Silvia Bresolin, Arianna Aricò, Stefano Comazzi, Maria Elena Gelain, Fulvio Riondato, Luca Bargelloni, Laura Marconato, Geertruy te Kronnie, Luca Aresu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24695110/pdf/?tool=EBI

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