Dysfunctional CFTR alters the bactericidal activity of human macrophages against Pseudomonas aeruginosa.

Dysfunctional CFTR alters the bactericidal activity of human macrophages against Pseudomonas aeruginosa.

Chronic inflammation of the lung, as a consequence of persistent bacterial infections by several opportunistic pathogens represents the main cause of mortality and morbidity in cystic fibrosis (CF) patients. Mechanisms leading to increased susceptibility to bacterial infections in CF are not complet...

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Main Authors: Paola Del Porto, Noemi Cifani, Simone Guarnieri, Enea Gino Di Domenico, Maria A Mariggiò, Francesca Spadaro, Silvia Guglietta, Marco Anile, Federico Venuta, Serena Quattrucci, Fiorentina Ascenzioni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625641/?tool=EBI

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