Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas

Facial high-risk basal cell carcinomas are preferably treated with Mohs micrographic surgery, but only 10% of patients are offered Mohs micrographic surgery in Sweden. The aim of this retrospective study was to examine the differences between primary and recurrent or incompletely excised facial high...

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Main Authors: Hannah Ceder, Malin Grönberg, John Paoli
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2021-02-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3698
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spelling doaj-7b162276850d48d58f8592051a71b2ce2021-02-02T13:26:47ZengSociety for Publication of Acta Dermato-VenereologicaActa Dermato-Venereologica0001-55551651-20572021-02-011012adv0038110.2340/00015555-36985944Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell CarcinomasHannah Ceder0Malin GrönbergJohn Paoli Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden. E-mail: hannah.ceder@vgregion.se. Facial high-risk basal cell carcinomas are preferably treated with Mohs micrographic surgery, but only 10% of patients are offered Mohs micrographic surgery in Sweden. The aim of this retrospective study was to examine the differences between primary and recurrent or incompletely excised facial high-risk basal cell carcinomas undergoing Mohs micrographic surgery, with regard to the number of stages, final defect sizes, reconstructive techniques and other consequences. The study was performed during the period 2012 to 2019 at our centre. A total of 903 basal cell carcinomas in 813 patients (70.1% primary, 10.4% incompletely excised and 19.5% recurrences) were included. The mean number of Mohs micrographic surgery stages was significantly lower for primary basal cell carcinomas compared with recurrences (p = 0.03), and the mean final defect size was significantly smaller in primary basal cell carcinomas compared with both recurrent (p < 0.0001) and incompletely excised (p = 0.003) tumours. Primary basal cell carcinomas tended to more often be reconstructed by primary closure (p = 0.08). Mohs micrographic surgery indications for facial high-risk basal cell carcinomas should be respected and used more frequently on primary basal cell carcinomas, in order to enable better utilization of resources and improved outcomes for the patient. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3698 basal cell carcinoma non-melanoma skin cancer mohs micrographic surgery recurrence incomplete excision
collection DOAJ
language English
format Article
sources DOAJ
author Hannah Ceder
Malin Grönberg
John Paoli
spellingShingle Hannah Ceder
Malin Grönberg
John Paoli
Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas
Acta Dermato-Venereologica
basal cell carcinoma
non-melanoma skin cancer
mohs micrographic surgery
recurrence
incomplete excision
author_facet Hannah Ceder
Malin Grönberg
John Paoli
author_sort Hannah Ceder
title Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas
title_short Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas
title_full Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas
title_fullStr Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas
title_full_unstemmed Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas
title_sort mohs micrographic surgery for primary versus recurrent or incompletely excised facial high-risk basal cell carcinomas
publisher Society for Publication of Acta Dermato-Venereologica
series Acta Dermato-Venereologica
issn 0001-5555
1651-2057
publishDate 2021-02-01
description Facial high-risk basal cell carcinomas are preferably treated with Mohs micrographic surgery, but only 10% of patients are offered Mohs micrographic surgery in Sweden. The aim of this retrospective study was to examine the differences between primary and recurrent or incompletely excised facial high-risk basal cell carcinomas undergoing Mohs micrographic surgery, with regard to the number of stages, final defect sizes, reconstructive techniques and other consequences. The study was performed during the period 2012 to 2019 at our centre. A total of 903 basal cell carcinomas in 813 patients (70.1% primary, 10.4% incompletely excised and 19.5% recurrences) were included. The mean number of Mohs micrographic surgery stages was significantly lower for primary basal cell carcinomas compared with recurrences (p = 0.03), and the mean final defect size was significantly smaller in primary basal cell carcinomas compared with both recurrent (p < 0.0001) and incompletely excised (p = 0.003) tumours. Primary basal cell carcinomas tended to more often be reconstructed by primary closure (p = 0.08). Mohs micrographic surgery indications for facial high-risk basal cell carcinomas should be respected and used more frequently on primary basal cell carcinomas, in order to enable better utilization of resources and improved outcomes for the patient.
topic basal cell carcinoma
non-melanoma skin cancer
mohs micrographic surgery
recurrence
incomplete excision
url https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3698
work_keys_str_mv AT hannahceder mohsmicrographicsurgeryforprimaryversusrecurrentorincompletelyexcisedfacialhighriskbasalcellcarcinomas
AT malingronberg mohsmicrographicsurgeryforprimaryversusrecurrentorincompletelyexcisedfacialhighriskbasalcellcarcinomas
AT johnpaoli mohsmicrographicsurgeryforprimaryversusrecurrentorincompletelyexcisedfacialhighriskbasalcellcarcinomas
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