Synthesis of a Spirocyclic Oxetane-Fused Benzimidazole
A new synthesis of 2-oxa-7-azaspiro[3.5]nonane is described. Spirocyclic oxetanes, including 2-oxa-6-azaspiro[3.3]heptane were converted into o-cycloalkylaminoacetanilides for oxidative cyclizations using Oxone® in formic acid. The expanded spirocyclic oxetane successfully gave the [1,2-a] ring-fuse...
Main Authors: | Michael Gurry, Patrick McArdle, Fawaz Aldabbagh |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/20/8/13864 |
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