Carbamazepine and Hyperpigmentation in a Young Woman: A Case Report
Carbamazepine(CBZ) is an effective first line treatment for trigeminal neuralgia and has an important place in the management of epilepsy and bipolar disorder. The potential for clinically important drug interactions exists because CBZ may induce the hepatic metabolism of other drugs or, conversely...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2020-11-01
|
| Series: | Case Reports in Clinical Practice |
| Subjects: | |
| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/341 |
| Summary: | Carbamazepine(CBZ) is an effective first line treatment for trigeminal neuralgia and has an important place in the management of epilepsy and bipolar disorder. The potential for clinically important drug interactions exists because CBZ may induce the hepatic metabolism of other drugs or, conversely, other drugs may induce or inhibit the metabolism of CBZ.CBZ is including big group of antiepileptic drugs that is widely used to prevent and control seizures. It has been associated with several cutaneous side effects, in this case reported a young woman who presented with dyspnea, weight loss, pancytopenia, abdominal pain and oligomenorrhea and two weeks history of hyperpigmented lesions over her face, neck and two hands. She had history of seizures and did well on carbamazepine for 7 months ago, carbamazepine was withdrawn and she was treated with local emollients. The lesions were partially improved in 2 weeks.
|
|---|---|
| ISSN: | 2538-2683 2538-2691 |