Dual Function Microtubule- and Mitochondria-Associated Proteins Mediate Mitotic Cell Death
Background: Survival and evolution of aneuploid cells after an asymmetric segregation of chromosomes at mitosis may be the common initiating event and underlying cause of the genetic diversity and adaptability of cancers. We hypothesize that mechanisms exist to detect impending aneuploidy and preven...
Main Authors: | Leyuan Liu, Rui Xie, Chaofeng Yang, Wallace L. McKeehan |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2009-01-01
|
Series: | Cellular Oncology |
Online Access: | http://dx.doi.org/10.3233/CLO-2009-0484 |
Similar Items
-
Acetylated microtubules are required for fusion of autophagosomes with lysosomes
by: Liu Leyuan, et al.
Published: (2010-11-01) -
Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis
by: Weimei Ruan, et al.
Published: (2019-01-01) -
Functional analyses of mitotic microtubule-binding complexes
by: Monda, Julie Kathryn
Published: (2019) -
The role of microtubule detyrosination in mitotic fidelity
by: Ana Luísa Teixeira Ferreira
Published: (2021) -
Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity
by: Carlos Sánchez-Huertas, et al.
Published: (2016-07-01)