An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species.
The C-terminal ends of small GTPases contain hypervariable sequences which may be posttranslationally modified by defined lipid moieties. The diverse structural motifs generated direct proteins towards specific cellular membranes or organelles. However, knowledge on the factors that determine these...
Main Authors: | Clara L Oeste, Mario Pinar, Kay O Schink, Javier Martínez-Turrión, Harald Stenmark, Miguel A Peñalva, Dolores Pérez-Sala |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4160200?pdf=render |
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