Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines

Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines

Real time quantitative reverse transcription PCR was used to monitor changes in apoptotic gene expression after treating cells with the DNA cross-linkers epichlorohydrin (ECH) and diepoxybutane (DEB). This article presents the data obtained from application of the comparative CT method to the amplif...

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Main Authors: Vanesa L. Silvestri, Julie T. Millard
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918306395
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spelling doaj-7b35d08f4db144b5b673e4dc49e2e6962020-11-25T02:47:28ZengElsevierData in Brief2352-34092018-08-0119932935Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell linesVanesa L. Silvestri0Julie T. Millard1Department of Chemistry, Colby College, Waterville, ME 04901, United StatesCorresponding author.; Department of Chemistry, Colby College, Waterville, ME 04901, United StatesReal time quantitative reverse transcription PCR was used to monitor changes in apoptotic gene expression after treating cells with the DNA cross-linkers epichlorohydrin (ECH) and diepoxybutane (DEB). This article presents the data obtained from application of the comparative CT method to the amplification of twelve apoptotic genes in human MCF10-A cells and eight genes in HUVEC cells. Further insight regarding the significance of these data can be found in “Cross-linking by epichlorohydrin and diepoxybutane correlates with cytotoxicity and leads to apoptosis in human leukemia (HL-60) cells” (Le et al., 2018) [1].http://www.sciencedirect.com/science/article/pii/S2352340918306395
collection DOAJ
language English
format Article
sources DOAJ
author Vanesa L. Silvestri
Julie T. Millard
spellingShingle Vanesa L. Silvestri
Julie T. Millard
Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines
Data in Brief
author_facet Vanesa L. Silvestri
Julie T. Millard
author_sort Vanesa L. Silvestri
title Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines
title_short Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines
title_full Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines
title_fullStr Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines
title_full_unstemmed Changes in apoptotic gene expression induced by the DNA cross-linkers epichlorohydrin and diepoxybutane in human cell lines
title_sort changes in apoptotic gene expression induced by the dna cross-linkers epichlorohydrin and diepoxybutane in human cell lines
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2018-08-01
description Real time quantitative reverse transcription PCR was used to monitor changes in apoptotic gene expression after treating cells with the DNA cross-linkers epichlorohydrin (ECH) and diepoxybutane (DEB). This article presents the data obtained from application of the comparative CT method to the amplification of twelve apoptotic genes in human MCF10-A cells and eight genes in HUVEC cells. Further insight regarding the significance of these data can be found in “Cross-linking by epichlorohydrin and diepoxybutane correlates with cytotoxicity and leads to apoptosis in human leukemia (HL-60) cells” (Le et al., 2018) [1].
url http://www.sciencedirect.com/science/article/pii/S2352340918306395
work_keys_str_mv AT vanesalsilvestri changesinapoptoticgeneexpressioninducedbythednacrosslinkersepichlorohydrinanddiepoxybutaneinhumancelllines
AT julietmillard changesinapoptoticgeneexpressioninducedbythednacrosslinkersepichlorohydrinanddiepoxybutaneinhumancelllines
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