Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice.

Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice.

Hypothalamic neurons expressing neuropeptide orexins are critically involved in the control of sleep and wakefulness. Although the activity of orexin neurons is thought to be influenced by various neuronal input as well as humoral factors, the direct consequences of changes in the activity of these...

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Bibliographic Details
Main Authors: Koh Sasaki, Mika Suzuki, Michihiro Mieda, Natsuko Tsujino, Bryan Roth, Takeshi Sakurai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3103553?pdf=render

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