Macrophage inhibits the osteogenesis of fibroblasts in ultrahigh molecular weight polyethylene (UHMWPE) wear particle-induced osteolysis

Macrophage inhibits the osteogenesis of fibroblasts in ultrahigh molecular weight polyethylene (UHMWPE) wear particle-induced osteolysis

Abstract Background In the ultrahigh molecular weight polyethylene (UHMWPE) prosthetic environment, fibroblasts affected by wear particles have the capacity of osteogenesis to reduce osteolysis. We aimed to assess the effects of macrophages on the osteogenic capability of fibroblasts treated with UH...

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Bibliographic Details
Main Authors: Pengfei Lei, Zixun Dai, Yu Shrike Zhang, Hua Liu, Wanting Niu, Kun Li, Long Wang, Yihe Hu, Jie Xie
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Ultrahigh molecular weight polyethylene
Wear particles
Fibroblast
Macrophage
Osteogenesis
Osteolysis
Online Access:http://link.springer.com/article/10.1186/s13018-019-1119-8

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