The basal forebrain contributes to cue-based spatial navigation performance inAlzheimer’s disease

The basal forebrain contributes to cue-based spatial navigation performance inAlzheimer’s disease

The basal forebrain degenerates in Alzheimer’s disease (AD) and this process is believed to contribute to the cognitive decline observed in AD patients. Impairment in spatial navigation is an early feature of the disease but whether basal forebrain dysfunction in AD is responsible for the impaired n...

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Bibliographic Details
Main Authors: Georg M Kerbler, Zuzana eNedelska, Jurgen eFripp, Jan eLaczó, Martin eVyhnalek, Jiri eLisy, Adam Scott Hamlin, Stephen E Rose, Jakub eHort, Elizabeth J Coulson
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
MRI
Alzheimer’s disease
navigation
cognitive impairment
basal forebrain
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00185/full

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