Extensive Genomic Variability of Knops Blood Group Polymorphisms is Associated with Sickle Cell Disease in Africa
Sickle cell disease (SCD) is a multisystem disorder characterized by chronic hemolytic anemia, vaso-occlusive crises, and marked variability in disease severity. Patients require transfusions to manage disease complications, with complements, directed by complement regulatory genes (CR1) and its pol...
Main Authors: | Kimberley C. Duru, Jenelle A. Noble, Aldiouma Guindo, Li Yi, Ikhide G. Imumorin, Dapa A. Diallo, Bolaji N. Thomas |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-01-01
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Series: | Evolutionary Bioinformatics |
Online Access: | https://doi.org/10.4137/EBO.S23132 |
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