Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymer
Deoxyribozymes (DNAzymes) having RNA-cleaving activity have widely been explored as tools for therapeutic and diagnostic purposes. Both the chemical cleaving step and the turnover step should be improved for enhancing overall activity of DNAzymes. We have shown that cationic copolymer enhanced DNAzy...
Main Authors: | Ken Saito, Naohiko Shimada, Atushi Maruyama |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2016-01-01
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Series: | Science and Technology of Advanced Materials |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/14686996.2016.1208627 |
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