Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine
Shikonin is an anthraquinone derivative extracted from the root of lithospermum. Shikonin is traditionally used in the treatment of inflammatory and infectious diseases such as hepatitis. Shikonin also inhibits proliferation and induces apoptosis in various tumors. However, the effect of shikonin on...
Main Authors: | Feng-Ying Zhang, Yi Hu, Zhong-You Que, Ping Wang, Yun-Hui Liu, Zhen-Hua Wang, Yi-Xue Xue |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-10-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/16/10/23823 |
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