Synthesis of C-Arylnucleoside Analogues
Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies...
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doaj-7bc24b4c86d14e3d9ec1ed5ed01c348b2020-11-25T02:27:15ZengMDPI AGMolecules1420-30492015-03-012034967499710.3390/molecules20034967molecules20034967Synthesis of C-Arylnucleoside AnaloguesChristophe Len0Gérald Enderlin1Sorbonne Universités, Université de Technologie de Compiègne, Ecole Supérieure de Chimie Organique et Minérale, Transformations Intégrées de la Matière Renouvelable, Centre de Recherche Royallieu, CS 60319, Compiègne cedex F-60203, FranceSorbonne Universités, Université de Technologie de Compiègne, Ecole Supérieure de Chimie Organique et Minérale, Transformations Intégrées de la Matière Renouvelable, Centre de Recherche Royallieu, CS 60319, Compiègne cedex F-60203, FranceModified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review.http://www.mdpi.com/1420-3049/20/3/4967C-arylnucleosidenucleosidecarbohydratetotal synthesisasymmetric catalysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Christophe Len Gérald Enderlin |
spellingShingle |
Christophe Len Gérald Enderlin Synthesis of C-Arylnucleoside Analogues Molecules C-arylnucleoside nucleoside carbohydrate total synthesis asymmetric catalysis |
author_facet |
Christophe Len Gérald Enderlin |
author_sort |
Christophe Len |
title |
Synthesis of C-Arylnucleoside Analogues |
title_short |
Synthesis of C-Arylnucleoside Analogues |
title_full |
Synthesis of C-Arylnucleoside Analogues |
title_fullStr |
Synthesis of C-Arylnucleoside Analogues |
title_full_unstemmed |
Synthesis of C-Arylnucleoside Analogues |
title_sort |
synthesis of c-arylnucleoside analogues |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2015-03-01 |
description |
Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review. |
topic |
C-arylnucleoside nucleoside carbohydrate total synthesis asymmetric catalysis |
url |
http://www.mdpi.com/1420-3049/20/3/4967 |
work_keys_str_mv |
AT christophelen synthesisofcarylnucleosideanalogues AT geraldenderlin synthesisofcarylnucleosideanalogues |
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1724843344470736896 |