Synthesis of C-Arylnucleoside Analogues

Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies...

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Main Authors: Christophe Len, Gérald Enderlin
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/3/4967
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spelling doaj-7bc24b4c86d14e3d9ec1ed5ed01c348b2020-11-25T02:27:15ZengMDPI AGMolecules1420-30492015-03-012034967499710.3390/molecules20034967molecules20034967Synthesis of C-Arylnucleoside AnaloguesChristophe Len0Gérald Enderlin1Sorbonne Universités, Université de Technologie de Compiègne, Ecole Supérieure de Chimie Organique et Minérale, Transformations Intégrées de la Matière Renouvelable, Centre de Recherche Royallieu, CS 60319, Compiègne cedex F-60203, FranceSorbonne Universités, Université de Technologie de Compiègne, Ecole Supérieure de Chimie Organique et Minérale, Transformations Intégrées de la Matière Renouvelable, Centre de Recherche Royallieu, CS 60319, Compiègne cedex F-60203, FranceModified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review.http://www.mdpi.com/1420-3049/20/3/4967C-arylnucleosidenucleosidecarbohydratetotal synthesisasymmetric catalysis
collection DOAJ
language English
format Article
sources DOAJ
author Christophe Len
Gérald Enderlin
spellingShingle Christophe Len
Gérald Enderlin
Synthesis of C-Arylnucleoside Analogues
Molecules
C-arylnucleoside
nucleoside
carbohydrate
total synthesis
asymmetric catalysis
author_facet Christophe Len
Gérald Enderlin
author_sort Christophe Len
title Synthesis of C-Arylnucleoside Analogues
title_short Synthesis of C-Arylnucleoside Analogues
title_full Synthesis of C-Arylnucleoside Analogues
title_fullStr Synthesis of C-Arylnucleoside Analogues
title_full_unstemmed Synthesis of C-Arylnucleoside Analogues
title_sort synthesis of c-arylnucleoside analogues
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2015-03-01
description Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review.
topic C-arylnucleoside
nucleoside
carbohydrate
total synthesis
asymmetric catalysis
url http://www.mdpi.com/1420-3049/20/3/4967
work_keys_str_mv AT christophelen synthesisofcarylnucleosideanalogues
AT geraldenderlin synthesisofcarylnucleosideanalogues
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