Chondroradionecrosis of the Larynx in a Patient with Laryngeal: A Case Report

• Main Authors: Aslan Ahmadi, Mohammad Mahdi Salem, Mahdi Safdarian, Shahriar Ilkhani, Roghaiieh Hamidian, Mostafa Cheraghipour, Ali Daneshvar, Farzad Izadi
• Format: Article
• Language: English
• Published: Mashhad University of Medical Sciences 2017-05-01
• Series: Iranian Journal of Otorhinolaryngology
• Subjects: Actinomycosis; Fistula; Larynx
• Online Access: http://ijorl.mums.ac.ir/article_8649_271fa34c3d80a1349a8fdee3500fa418.pdf

Introduction: Actinomycosis of the larynx has been rarely reported in the literature and usually occurs in patients with a history of laryngeal carcinoma and radiation therapy. However, its co-existence with chondroradionecrosis due to radiotherapy is even rarer. The most common site of infection is the cervicofacial region, especially in the submandibular area.   Case Report: Here we report a 63-year-old male with a history of chemoradiotherapy because of laryngeal cancer 1 year earlier who presented with laryngeal actinomycosis. After prolonged penicillin-based treatment, the patient underwent thyroid cartilage defect reconstructive surgery because of a laryngocutaneous fistula due to chondroradionecrosis. The diagnosis, work-up, and management of the case are discussed, as well as a review of the literature.   Conclusion: Although actinomycotic infection of the larynx is rare, it should be considered in the differential diagnosis of laryngeal complaints, especially in immunocompromised patients.