Decreased Expression of TLR-9 and Cytokines in the Presence of Bacteria in Patients with Otitis Media with Effusion

Decreased Expression of TLR-9 and Cytokines in the Presence of Bacteria in Patients with Otitis Media with Effusion

ObjectivesToll-like receptor (TLR)-9 recognizes unmethylated cytidine-phosphate-guanosine (CpG) motifs in bacteria. Therefore, the expression of TLR-9 may differ according to the results of bacterial culture, and thus a change in proinflammatory cytokine induction can also be expected. The authors a...

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Bibliographic Details
Main Authors: Ho Yun Lee, Young Il Kim, Jin Woo Lee, Jae Yong Byun, Moon Suh Park, Seung Geun Yeo
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2013-12-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Toll-like receptor
Bacteria
Innate immunity
Cytokine
Nitric oxide synthase
Online Access:http://www.e-ceo.org/upload/pdf/ceo-6-195.pdf

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