The aldosterone-mineralocorticoid receptor pathway exerts anti-inflammatory effects in endotoxin-induced uveitis.
We have previously shown that the eye is a mineralocorticoid-sensitive organ and we now question the role of mineralocorticoid receptor (MR) in ocular inflammation. The endotoxin-induced uveitis (EIU), a rat model of human intraocular inflammation, was induced by systemic administration of lipopolys...
Main Authors: | Elodie Bousquet, Min Zhao, André Ly, Guillaume Leroux Les Jardins, Brigitte Goldenberg, Marie-Christine Naud, Laurent Jonet, Bernadette Besson-Lescure, Frederic Jaisser, Nicolette Farman, Yvonne De Kozak, Francine Behar-Cohen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3494666?pdf=render |
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